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子宫内膜间质肉瘤中Ki-67的表达水平与组织学分级的关系
引用本文:王忠英,李宗敏,胡玉莲,王刚平. 子宫内膜间质肉瘤中Ki-67的表达水平与组织学分级的关系[J]. 中国临床实用医学, 2010, 4(2): 70-71. DOI: 10.3760/cma.j.issn 1673-8799.2010.04.36
作者姓名:王忠英  李宗敏  胡玉莲  王刚平
作者单位:1. 日照市人民医院妇产科,276826
2. 日照市东港医院妇产科
3. 日照市人民医院病理科,276826
摘    要:目的探讨子宫内膜间质肉瘤中Ki-67的表达水平与组织学分级的关系。方法对确诊的24例子宫内膜间质肉瘤和12例未分化子宫内膜肉瘤用免疫组化法检测Ki-67的表达情况,并分析与患者年龄、肿瘤大小、淋巴结及远处转移、恶性度的关系。结果Ki-67指数在子宫内膜间质肉瘤和未分化子宫内膜肉瘤中分别为38%、87%,差异有统计学意义(P〈0.05);而与患者年龄、肿瘤大小、淋巴结及远处转移无关(P〉0.05)。结论Ki-67增殖指数和恶性度分级呈正相关,可能是判断危险度的指标。

关 键 词:子宫内膜间质肉瘤  Ki-67核抗原  分级

Expression of Ki-67 and its relationship with the histological grade of Endometrial Stromal Sarcomas
RUAN Luo-yang,XU Xiao-hong,XU Xiao-meng. Expression of Ki-67 and its relationship with the histological grade of Endometrial Stromal Sarcomas[J]. China Clinical Practical Medicine, 2010, 4(2): 70-71. DOI: 10.3760/cma.j.issn 1673-8799.2010.04.36
Authors:RUAN Luo-yang  XU Xiao-hong  XU Xiao-meng
Affiliation:WANG Zhong-ying,LI Zong-min,HU Yu-lian ,et al( Department of ynecology and obstetrics, The People' s Hospital of Rizhao City,Shandong Province 276826,China)
Abstract:Objective To study the expression of Ki-67 and its relationship with the histological grade of Endometrial Stromal Tumors. Methods Immunohistochemical EnVision method was applied to detect the expression of Ki-67 expression in 24 cases of Endomertrial stromal sarcoma( ESS), and 12 cases of Undifferentiated endometrial sarcoma(UESs) ,and its relationship with the risk rank was analyzed. Results The Ki-67 nuclear antigen in ESSs were 38% which were lower than 87% in UESs( P < 0.05 ). There was posive correlation of Ki-67 with histolegical grade between ESS and UES. Conclusion The expression of Ki-67 might be important biological markers for histolegical grade of ESSs.
Keywords:KangboningRopivacaineBupivacaineBlock anesthesia of cervical plexus
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