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Primary pancreatic lymphoma diagnosed by endoscopic ultrasound-guided fine needle biopsy
Authors:Ning-Xin Zhu  Xiao-Yan Wang  Ting Tong  Jia-Hao Xu  Yuan-Yuan Yang  Li Tian
Affiliation:1. Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA;2. Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA;3. Center for Biostatistics, Department of Biomedical Informatics, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA;1. Department of Gastroenterology, Santa Luzia Hospital - Unidade Local de Saúde Alto Minho, Viana do Castelo, Portugal;2. Department of Gastroenterology, Professor Doutor Fernando Fonseca Hospital, Amadora, Portugal;3. Department of Gastroenterology, Nova Medical School/Faculty of Medical Sciences, Lisbon, Portugal;4. University Center of Gastrenterology - Hospital Cuf Tejo, Lisbon, Portugal;5. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal;6. ICVS/3B''s - PT Government Associate Laboratory, Braga/Guimarães, Portugal
Abstract:To the Editor:Primary pancreatic lymphoma (PPL) is extremely rare, account- ing for 1% of extra-nodal lymphomas and less than 0.5% of pan- creatic masses [1] . Both cytological and histological analyses are required to confirm the diagnosis of PPL. The main treatments include chemotherapy and radiotherapy [2] . Pancreatic resection alone does not improve the survival rate [3] . Hence, it is necessary to differentiate PPL from other malignant tumors before surgery. To date, there is no consensus on the optimal diagnostic approach and most experience is from case reports.
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