妊娠期单纯低甲状腺素血症的危险因素和对母婴结局的影响

妊娠期单纯低甲状腺素血症又称妊娠期低甲状腺素(thyroxine,T4)血症,是指妊娠妇女甲状腺自身抗体阴性、血清促甲状腺激素(thyroid stimulating hormone,TSH)水平正常但血清游离甲状腺素(free thyroxine,FT4)水平低于妊娠期特异性参考范围下限.目前,妊娠期低T4血症的病因...

Risk Factors of Gestational Isolated Hypothyroxinemia and Its Effect on Maternal and Infant Outcomes

Gestational isolated hypothyroxinemia, also known as gestational hypothyroxinemia, refers to pregnant women with negative thyroid autoantibodies, normal thyroid stimulating hormone (TSH) level but lower free thyroxine (FT₄) level than the lower limit of specific reference range during pregnancy. At present, the etiology of gestational isolated hypothyroxinemia is unclear. Whether it will increase the risk of gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), preterm birth and other adverse outcomes of pregnancy remains controversial. Whether gestational isolated hypothyroxinemia affects the intelligence and nervous system development of offspring is still controversial. Therefore, one of the methods to solve the dispute is to carry out a multicenter research and longer follow-up visit to pregnant women with gestational isolated hypothyroxinemia and their offspring.