子宫碰撞瘤的研究进展

子宫碰撞瘤是一种由2种或2种以上恶性肿瘤组成的罕见病理类型,相关报道较少。其病因及发病机制尚不明确,临床表现、影像学检查均不具有特异性,术前诊断困难,目前主要依靠病理学检查来作出准确诊断。子宫碰撞瘤组织学类型多样,至今仍未建立起规范化治疗指南,多采用以手术和放疗为主、化疗为辅的综合治疗,预后差异较大。近年来,子宫恶性肿瘤的发病率日益增加,随着免疫组织化学、蛋白质印迹（Western blotting）和聚合酶链反应（PCR）等实验技术在临床病理学中的广泛运用,子宫碰撞瘤的检出率有所提升。现从子宫碰撞瘤的临床特征、诊断与治疗等方面进行综述,以期增加人们对子宫碰撞瘤的全面了解,及早作出准确的诊断,进而实施临床干预措施,改善患者的预后。

Research Progress of Uterine Collision Tumor

Uterine collision tumor is a rare pathological type composed of two or more malignant tumors with few related reports.Its etiology and pathogenesis are still unclear.Clinical manifestations and imaging examinations are not specific,and preoperative diagnosis is difficult,mainly rely on pathological examination to make an accurate diagnosis.There are various histological types of uterine collision tumors,while no standardized treatment guidelines have been established so far.The comprehensive treatment mainly consists of surgery and radiotherapy,supplemented by chemotherapy,and the prognosis is quite different.In recent years,the incidence of uterine malignant tumors has been increasing.With the extensive use of experimental techniques such as immunohistochemistry,Western blotting,and polymerase chain reaction(PCR)in clinical pathology,the detection rate of uterine collision tumors has been increased.This article reviews the clinical features,diagnosis and treatment of uterine collision tumors,in order to increase people′s comprehensive understanding of uterine collision tumors,making early and accurate diagnosis,and implement clinical intervention measures to improve the prognosis of patients.