基于国产与进口精确放疗设备在原发性肝癌与胰腺癌的临床剂量学评价研究

目的 对比国产及进口精确放疗设备应用于原发性肝癌与胰腺癌放疗剂量学特点,评估国产精确放疗设备的临床应用情况.方法 回顾性选取原发性肝癌(分为小肝癌和大肝癌)、胰腺癌患者各60例,对选取病例分别进行静态调强计划设计.采用加速器设备的不同将患者计划分为进口组和国产组.评估计划剂量学参数并实施剂量验证.结果 所有计划靶区和危...

Dosimetric Evaluation of Domestic and Imported Precision Radiotherapy Equipment in Primary Hepatocellular Carcinoma and Pancreatic Cancer

Objective The application of domestic and imported precision radiotherapy equipment in primary hepatocellular carcinoma and pancreatic cancer was compared to evaluate the operation of domestic precision radiotherapy equipment.Methods A total of 60 patients with primary hepatocellular carcinoma(divided into small and large hepatocellular carcinoma),and pancreatic cancer were selected retrospectively.IMRT plans were designed for selected cases.All plans were divided into domestic and imported groups.The planed dosimetry parameters and dose verification results were evaluated.Results The targets and organ at risk(OAR)of all research plans could meet the limited requirements.The homogeneity index(HI)of patients with primary hepatocellular carcinoma the domestic group was better than the imported group(P<0.05).There was no statistically significant difference in conformal index(CI)between all the groups(P>0.05).There was no statistical difference between the V₁₀ and V₃₀ of liver in the domestic group compared with the imported group(P>0.05).For the primary hepatocellular carcinoma plans,imported group liver D_mean was significantly lower than the domestic group(P<0.05).The spinal cord D_max of small hepatocellular carcinoma in domestic group was significantly lower than that in imported group(P<0.05).All dose verification results could meet the clinical requirements.Conclusion Compared with the imported equipment,the domestic equipment can complete the design and implementation of the conventional IMRT plan.the plan quality and dose verification results are in good agreement with the imported equipment.Domestic radiotherapy equipment can basically meet the clinical needs.