基于RT-Mind软件的乳腺癌靶区及危及器官的自动勾画

目的 探讨RT-Mind软件在乳腺癌临床靶区(Clinical Target Volumes,CTV)及危及器官(Organs-At-Risk,OARs)自动勾画的可行性,为临床应用提供依据.方法 选取10例乳腺癌保乳术后放疗患者,由临床医生手动勾画CTV及OARs(左肺、右肺、心脏及健侧乳腺),并以此勾画结果作为参考...

Automatic Delineation of Breast Cancer Target Area and Organs-at-risk Using RT-Mind Software

Objective To explore the feasibility of RT-Mind software for the automatic delineation of clinical target volumes(CTV)and organs-at risk(OARs)in the radiotherapy for breast cancer so as to provide a basis for the clinical application.Methods A total of 10 patients with breast cancer after breast-conserving surgery were delineated for the CTV and OARs(L-lung,R-lung,heart,healthy breast)by an experienced radiation oncologist,and the contouring results were defined as the reference standard.And then the CTV and OARs were automatic delineation by RT-Mind software.Several evaluation parameters such as Dice coefficient(DSC),Jaccard coefficient(JAC),Hausdroff distance(HD),and volume difference(VD)were used to evaluate the contouring results.Results The DSC,JAC,VD,HD values of automated delineation of CTV were 0.77±0.06,0.64±0.07,(33.47±18.66)%,(2.53±0.64)cm,respectively.The DSC,JAC,VD,HD values of automated delineation of CTV which retracted along the Body by 0.5 cm(CTV_(retracted 0.5 cm))were 0.83±0.05,0.71±0.07,(17.12±12.11)%,(2.53±0.64)cm,respectively.Compared with automated delineation CTV,CTV_(retracted 0.5 cm) can significantly improve the evaluation parameters,except for the value of HD.The HD values of four organs-at risk were less than 2.00 cm.Comparison of DSC,JAC,and VD values of four OARs:lungs>heart>contralateral breast,indicating the effect of automatic delineation were lungs>heart>contralateral breast.Conclusion RT-Mind software can accurately realize the automatic delineation of OARs in radiotherapy for breast cancer.For CTV in breast caner,the effect of automatic delieating of RT-Mind software is not ideal.When the CTV is retracted along the Body by 0.5 cm,the effect of automatic delieating for CTV can significantly improved.RT-Mind software can save time and improve the working efficiency for clinical doctors.