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Economic burden of gastro-oesophageal reflux disease and dyspepsia: A community-based study
Authors:Bijan Moghimi-Dehkordi  Mohsen Vahedi  Babak Khoshkrood Mansoori  Amir Kasaeian  Azadeh Safaee  Manijeh Habibi  Asma Pourhoseingholi  Mohammad Amin Pourhoseingholi  Mohammad Reza Zali
Institution:1. Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Science, Tehran, Iran;2. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Science, Tehran, Iran;1. Laboratory of Theoretical Chemistry, Department of Chemistry, University of Maragheh, P.O. Box: 5513864596, Maragheh, Iran;2. School of Chemistry, University College of Science, University of Tehran, Tehran, Iran;1. Department of microbiology, Karaj branch, Islamic Azad university, Karaj, Iran;2. Department of microbiology, Iran university of medical sciences and health services, Tehran, Iran;1. Northern Centre for Cancer Care, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK;2. The Royal College of Radiologists, London, UK;3. Velindre Cancer Centre, Cardiff, UK;4. Leeds Cancer Centre, Leeds, UK;5. Aberdeen Royal Infirmary, Aberdeen, UK;7. The Christie NHS Foundation Trust, Manchester, UK;11. NHS Highlands, Inverness, UK;1. Department of Obstetrics and Gynecology, French Trophoblastic Disease Reference Center, Lyon Sud University Hospital, Lyon 1 Claude Bernard University, Pierre-Bénite, France;2. Cancer Center Alexis Vautrin, Vandoeuvre-les-Nancy, France;3. Charing Cross Gestational Trophoblastic Disease Centre, Charing Cross Hospital, Campus of Imperial College London, London, United Kingdom;1. University of Cologne, Department of Otorhinolaryngology, Head and Neck Surgery, Germany;2. University of Cologne, Institute for Clinical Chemistry, Germany
Abstract:Background and study aimsGastro-oesophageal reflux disease (GERD) and dyspepsia are common digestive disorders that inflict serious harm, burden and economic consequences on individuals worldwide. The aim of this study was to estimate the direct and indirect economic burden of GERD and dyspepsia in the whole population of Tehran, the capital of Iran.Patients and methodsThe study was performed on a total of 18,180 adult subjects (age > 18 years) taken as a random sample in Tehran province, Iran (2006–2007). A valid and reliable questionnaire was used to enquire about the symptoms of GERD, dyspepsia and the frequency of the utilization of health services including physician visits, hospitalisations and productivity loss due to GERD/dyspepsia symptoms in the preceding 6 months.ResultsGERD was found in 518 (41.9% males) patients and dyspepsia in 404 patients (38.9% males). Further 1007 subjects had both GERD and dyspepsia. The total direct costs of disease per patient for GERD, dyspepsia and their overlap were PPP$97.70, PPP$108.10 and PPP$101.30, respectively (PPP, purchasing power parity dollars). The total indirect cost of disease per patient was PPP$13.7, PPP$12.1 and PPP$32.7, for GERD, dyspepsia and their overlap, respectively.ConclusionAccording to our results, hospitalisation and physician visits were the main cost of disease that could be minimised by revision of the insurance business in Iran.
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