| 利用实时反向转录PCR的分子定量监测TEL-AML1+儿童急性淋巴细胞性白血病的治疗反应和缓解状况 |
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| 引用本文： | K.Seeger,K.-A.Kreuzer,U.Lass,T.Taube,D.Buchwald,C.Eckert,G.K.利用实时反向转录PCR的分子定量监测TEL-AML1+儿童急性淋巴细胞性白血病的治疗反应和缓解状况[J].中德临床肿瘤学杂志,2001,18(6). |
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| 作者姓名： | K.Seeger K.-A.Kreuzer U.Lass T.Taube D.Buchwald C.Eckert G.K |
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| 作者单位： | Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，Department of Pediatric Oncology/Hematology，Otto-Heubner-Centrum，Charite Medical Center，Campus Virchow，Humboldt-University at Berlin，暨南大学医学院血液病研究所 Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany，Augustenburger Platz 1，D-13353 Berlin，Germany |
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| 摘 要： | 运用分子生物学技术及流式细胞术,对治疗反应和微小残留白血病病灶(MRD)进行灵敏的定量分析,可以更加可靠地预测儿童急性淋巴细胞性白血病(ALL)患者的预后及复发风险。分子水平的研究大多数利用T细胞受体(TCR)和免疫球蛋白基因重排作为唯一克隆特异性标志来监测MRD,但这种DNA水平上的研究方法时间长、费用高而且工作量大。在儿童
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