| 旱莲草水提物对小鼠的抗炎镇痛作用 |
| |
| 引用本文： | 王晓丹,史桂云,辛晓明,曹明亮,朱玉云,高允生.旱莲草水提物对小鼠的抗炎镇痛作用[J].泰山医学院学报,2005,26(6):558-559. |
| |
| 作者姓名： | 王晓丹 史桂云 辛晓明 曹明亮 朱玉云 高允生 |
| |
| 作者单位： | 1. 泰山医学院药学院,山东,泰安,271000
2. 泰山医学院附属医院,山东,泰安,271000 |
| |
| 摘 要： | 目的 观察旱莲草（HEP）水提物的抗炎镇痛作用。方法 采用二甲苯致炎法、光辐射热甩尾法、冰醋酸扭体法观察早莲草灌胃给药后对小鼠的抗炎镇痛作用。结果 HEP水提物能明显抑制二甲苯所致的小鼠耳廓炎性肿胀，对光热辐射所致的小鼠疼痛和冰醋酸所致的小鼠扭体反应均有显著抑制作用。结论 旱莲草具有显著的抗炎镇痛作用。
|
| 关 键 词： | 旱莲草 抗炎 镇痛 |
| 文章编号： | 1004-7115（2005）06-0558-02 |
| 收稿时间： | 2005-08-11 |
| 修稿时间： | 2005年8月11日 |
Anti-inflammatory and analgesic effects of Herba eclipta prostrata aqueous extract on mice |
| |
| WANG Xiao-dan,SHI Gui-yun,XIN Xiao-ming,CAO Ming-liang,ZHU Yu-yun,GAO Yun-sheng.Anti-inflammatory and analgesic effects of Herba eclipta prostrata aqueous extract on mice[J].Journal of Taishan Medical College,2005,26(6):558-559. |
| |
| Authors: | WANG Xiao-dan SHI Gui-yun XIN Xiao-ming CAO Ming-liang ZHU Yu-yun GAO Yun-sheng |
| |
| Institution: | 1. Dept. of Pharmacology, Taishan Medical College, Taian 271000, China; 2. Affiliated Hospital of Taishan Medical College, Taian 271000, China |
| |
| Abstract: | Objective: To investigate the anti-inflammatory and analgesic effects of herba eliptae prostrata aqueous extract. Methods: After the mice were given HEP 15g/kg, 30g/kg, ig, the anti-inflammatory and analgesic effects of HEP were observed by means of dimethylbenzene inducing ear edema model, acetic acid inducing writhing model and light hot method. Results: It was found that the mouse' s ear edema induced by dimethylbenzene was evidently suppressed by HEP. At the same time, the writhing reaction, induced by antimony potassium tartrate was inhibited and the pain threshold induced by light hot was increased significantly in mice. Conclusion: HEP has notable effects on antiinflamma-tion and analgesia. |
| |
| Keywords: | herba eclipta prostrata anti-inflammation analgesia |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
