| 母亲、脐带及新生儿百日咳、白喉、破伤风抗体的效价测定 |
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| 引用本文： | 宋淑嫒,二井立惠,神谷齐,樱井实.母亲、脐带及新生儿百日咳、白喉、破伤风抗体的效价测定[J].现代免疫学,1986(1). |
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| 作者姓名： | 宋淑嫒 二井立惠 神谷齐 樱井实 |
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| 作者单位： | 北京市儿童医院
(宋淑嫒)，日本三重大学儿科
(二井立惠，神谷齐)，日本三重大学儿科(樱井实) |
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| 摘 要： | 本文用ELISA法探讨母子之间百日咳、白喉,破伤风抗体效价移行情况,以及新生儿后期抗体效价下降的程度。结果表明,正常母体与脐带血中抗LPF、FHA、白喉、破伤风类毒素效价之间密切相关,而生后1个月的婴儿血中抗体效价明显低于脐血抗体。
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THE TITER OF ANTIBODIES AGAINST DPT IN THE BLOOD OF MOTHER,UMBILICAL CORD AND NEWBORN |
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| Abstract: | This paper presents the investigation of the possible transfer of antibodies against pertussis, diphtheria and tetanus from the mother to the offspring and the lowering of the titer of antibodies in the newborn using ELISA method. It was found that there existed a close relationship between the titers of the antibodies against LPF, FHA, diphtheria, and tetanus in the blood of mother and umbilical cord. Thus, the titer of the antibodies in the blood of infants by the age of one month was apparently lower than that of the umbilical cord. It is necessary, therefore, to investigate the titer of antibodies against LPF and FHA in a normal pregnant woman. In case the antibody titer being lower than 0.2 Eu/ml and 2 Eu/ml for anti-LPF and anti-FHA respectively, administration refined pertussis vaccine to the expecting mother should be carried out to enhance the antibody titer so as to guard the newborn from pertussis. |
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