孕妇血清风疹病毒抗体IgM检测的临床意义

目的探讨孕妇血清风疹病毒IgM抗体检测的临床价值。方法采用酶联免疫吸附法（ELISA）检测230例孕妇血清中的风疹病毒特异性抗体IgM。结果230例中IgM阳性20例，阳性率为8．70％；多次妊娠者IgM阳性率（25．93％）明显高于初次妊娠者（6．40％）（χ^2=11．43，P〈0．05）；IgM阳性孕妇的早期流产率为31．58％（6／19），而IgM阴性孕妇的早期流产率为8．53％（11／129），两者比较差异有统计学意义（P〈0．05）。结论孕妇血清风疹病毒IgM抗体的测定有助于预测妊娠结局、降低先天性风疹综合征患儿的出现率。

The clinical value of detecting RV-IgM antibody in sera of pregnant women

Objective To investigate the clinical value of detecting RV4gM antibody in sera of preg- nant women. Methods Enzyme-linked immunosorbent assay（ELISA） was used to detect RV-IgM specific an- tibody in sera of pregnant women. Results The positive rate of RV-IgM of the 230 pregnant women were 8.70% （20/230） ;The positive rate of RV-IgM in mnhigravida （25.93%） was markedly higher than primigravid women （ 6.40% ） （χ^2 = 11.43, P 〈 0. 05 ） ; The early abortion rate of IgM-positive pregnant women was 31.58% （6/19） , whereas IgM-negative pregnant women was 8.53% （ 11/129 ） （χ^2 = 8. 65, P 〈0. 05 ）. Conclusion the detection of RV-IgM specific antibody in sera of pregnant women will help to predict pregnancy outcome, and reduce the frequency of congenital rubella syndrome infant.