| 均匀设计定量资料有多个应变量时的分析方法 |
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| 引用本文： | 郭秀花,杨兴华,罗艳侠,周诗国.均匀设计定量资料有多个应变量时的分析方法[J].解放军药学学报,2005,21(5):391-393. |
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| 作者姓名： | 郭秀花 杨兴华 罗艳侠 周诗国 |
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| 作者单位： | 首都医科大学,公共卫生与家庭医学学院流行病与卫生统计学系,北京,100069;中国人民解放军军事医学科学院,北京,100850 |
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| 摘 要： | 目的探讨在药品研发中利用均匀设计安排试验后,数据中的多个自变量与多个应变量间的关联性.方法介绍典型相关的原理,并用实例说明实现方法.结果实例中6个自变量、4个应变量经典型相关分析后,整体关联性较大的各有2个变量.结论探讨多个自变量与多个应变量间的整体关联性,为药品研发中利用均匀设计安排试验后进行数据分析,提供了一种新的数学模型.
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| 关 键 词： | 药品研发 均匀设计 典型相关 |
| 文章编号： | 1008-9926（2005）05-0391-03 |
| 收稿时间： | 2004-05-13 |
| 修稿时间： | 2004-06-17 |
An Analytic Method of Many Independent Variables in Arranging Experiment By Uniform Design in Developing Medicine |
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| GUO Xiu-Hua,YANG Xing-Hua,LUO Yan-Xia,ZHOU Shi-Guo.An Analytic Method of Many Independent Variables in Arranging Experiment By Uniform Design in Developing Medicine[J].Pharmaceutical Journal of Chinese People's Liberation Army,2005,21(5):391-393. |
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| Authors: | GUO Xiu-Hua YANG Xing-Hua LUO Yan-Xia ZHOU Shi-Guo |
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| Abstract: | Aim To explore the relationship between many dependent variables and many independent variables in arranging experiment by uniform design in developing medicine. Methods The theory of canonical correlation was briefed and the method of canonical correlation was adopted for the example in uniform design. Results After the example with 6 dependent variables and 4 independent variables was analyzed using canonical correlation, there were 2 variables respectively that were interrelated significantly. Conclusiom Exploring the relationship between many dependent variables and many independent variables, can provide a profitable mathematical model in arranging experiment by uniform design in developing medicine. |
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| Keywords: | Develop medicine Uniform design Canonical correlation |
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