腮腺多形性腺瘤癌变的病理学观察

544例腮腺多形性腺瘤中，恶性18例，占3．3％，其中癌变16例，原发性恶性多形性腺癌2例。除细胞间变外，具有肿瘤的侵袭性及快速增殖的特征：包膜浸润、侵犯邻近组织、血管内瘤栓、核分裂象增多等对诊断更有意义。在526例良性痛中女性多见，计有315例，占59．8％，年龄多为20～52岁；而此痛伴癌变者16例中以男性居多11例，占68.8％，常见于50岁以上。组织学类型，未分化癌居多，占43．7％，而腺癌仅占31．2％，一般未分化癌预后较差。

Histopathological observation of carcinomas on pleomorphic adenomas of parotid

Five hundred and forty-four patients of pleomorphic adenomas ofparotid were studied. Of all cases, 18 were malignant (3. 3 % ) among Which 16 carcino-mas, 2 primary malignant pleomorphic adenomas. The pathological features of carcino-mas were capsular infiltration,invasion into adjacent tissues,embolism in blood vesselesand increasing in mitotic figures which were significant for diagnosis of carcinomas ofpar0tid pleomorphic adenomas because these feature suggested cellular atypism,aggres-sive characteristic and high-speed multiplication. In the 526 cases benign pleomorphicadenomas, 3l5 cases were found in females aged from 3O to 49 (59. 8 % ),whereas,in 16carcinomas pleomorphic adenomas, 11 were males aged over 50. The prognosis of undif-ferentiated types was poor.