神经阻滞联合加巴喷丁治疗带状疱疹后神经痛

目的采用加巴喷丁联合神经阻滞治疗PHN，观察其疗效。方法将46例PHN患者随机分为2组，每组23例，分别接受神经阻滞（A组）和神经阻滞联合口服加巴喷丁治疗（B组），用视觉模拟评分（VAS）、口述评分（VRS）、六点行为活动评分（BRS—S）及睡眠时间评定近期疗效，观察并发症及药物副作用。结果在4周观察期间．两组患者治疗后各时点与治疗前相比疼痛评分随时间下降，睡眠时问增加（P〈0．05）。B组的疼痛评分下降大于A组，24h睡眠时间增加大于A组（P〈0．05）．两组未出现并发症及严重的药物的副作用。结论神经阻滞联合加巴喷丁治疗较单独使用神经阻滞的治疗效果更好。

Nerve block combined with antiepileptic drug gabapentin for the patients with post - herpetic neuralgia

Objective To observe the effects of nerve block combined with antiepileptic drug gabapentin on the patients with post - herpetic neuralgia （ PHN ）. Methods 46 persons suffering from PHN had been randomly divide into two groups （ group A and B ） received nerve block （ group A） or nerve block combine with gabapentin （ group B ）. The effects were evaluated by VAS, VRS, BRS - S and sleeping time, and observed the side effects and complications. Results The pain scores after treatment decreased with time comparing with that before treatment within each group, sleeping time increased （ P 〈 0.05 ）, but B group was more obvious than A group （P 〈 0.05 ）. All the groups hadn＇t evident side effects and complications occurred. Conclusion The two methods of treatment have evident effects, but nerve block combine gabapentin are better than nerve block alone.