慢性前列腺炎患者血清抗精子抗体和精液参数变化 |
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引用本文: | 霍山,谢群,方小武,彭文标,蒋善福.慢性前列腺炎患者血清抗精子抗体和精液参数变化[J].中国综合临床,2004,20(6):538-539. |
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作者姓名: | 霍山 谢群 方小武 彭文标 蒋善福 |
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作者单位: | 1. 528403,广东省中山市博爱医院泌尿外科,中山市南朗医院外科 2. 528403,广东省中山市博爱医院泌尿外科 |
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摘 要: | 目的 探讨前列腺慢性炎症对患者血清抗精子抗体 (AsAb)和精液参数的影响。方法 用酶联免疫吸附试验 (ASA ELISA)对 75例慢性前列腺炎患者和 31例正常对照者血清中AsAb进行定量分析 ,用美国HML全自动精液分析仪对两组精液常规检查 ,比较血清AsAb和精液主要参数变化。结果 慢性前列腺炎患者血清抗精子抗体IgG、IgA值明显高于正常对照组 (P <0 .0 1) ,精液量、精子活动百分率、精子正常形态百分率、精子活力a级和a b级、路径速度 (VAP)、直线运动速度 (VSL)及前向性STR均显著低于正常生育者 (P <0 .0 5和P <0 .0 1) ,精子密度、精液PH值、侧摆幅值 (ALH)与正常对照者比较无显著性差异 (P>0 .0 5 )。结论 慢性前列腺炎患者血清抗精子抗体滴度升高 ,精液部分主要参数较正常生育者明显降低。
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关 键 词: | 前列腺炎 慢性 血清抗精子抗体 精液 |
文章编号: | 1008-6315(2004)06-0538-02 |
修稿时间: | 2004年1月6日 |
Changes of serum antisperm antibody and sperm parameters of chronic prostatitis patients |
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Institution: | 5284039 Zhongshan |
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Abstract: | Objective To explore the influence of chronic prostatitis to serum antisperm antibody(AsAb) and sperm parameters.Methods AsAb in 75 chronic prostatitis patients and 31 normal controls was analyzed by enzyme-linked immunoabsorbent assay(ELISA).Routine examination was made for the sperm in two groups by American HML auto-sperm analyzer to compara the changes of AsAb and sperm parameters.Results IgG and IgA levels in chronic prostatitis patients were obviously higher than those of normal controls(P<0.01) but the volume of sperm,the activity percentage of sperm,the normal morphology percentage of sperm,the activity a grade and (a b)grade of sperm,VAP,VSL and STR were remarkably lower than those of normal controls(P<0.05 and P<0.01 ).There was no significant difference in sperm density,PH and ALH of sperm between two groups(P>0.05).Conclusion AsAb titer of chronic prostatitis patients is increased but the major parameters of sperm are decreased,compared with normal controls. |
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Keywords: | Prostatitis chronic Serum anti-sperm antibody Sperm |
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