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急性冠脉综合征患者血清肌钙蛋白Ⅰ和血清脑钠肽水平及其意义
引用本文:张惠军,郭喜朝,高凌根,李倩,夏杨. 急性冠脉综合征患者血清肌钙蛋白Ⅰ和血清脑钠肽水平及其意义[J]. 河北医学, 2010, 16(11): 1342-1343. DOI: 10.3969/j.issn.1006-6233.2010.11.0025
作者姓名:张惠军  郭喜朝  高凌根  李倩  夏杨
作者单位:武警北京总队医院,北京,100027
摘    要:目的:探讨血清肌钙蛋白Ⅰ和血清脑钠肽水平对急性冠脉综合征(ACS)的临床意义。方法:以ACS患者78例和稳定性心绞痛患者(SAP)40例为研究对象,将ACS患者分为不稳定性心绞痛(UAP)组、急性心肌梗死(AMI)组,测定其血清肌钙蛋白Ⅰ和血清脑钠肽水平。结果:ACS组血清肌钙蛋白Ⅰ(CTNI)和血清脑钠肽(BNP)水平明显高于SAP组(P〈0.01),AMI组血清肌钙蛋白I(CTNI)和血清脑钠肽(BNP)水平明显高于UAP组(P〈0.01)。结论:血清肌钙蛋白Ⅰ(CTNI)和血清脑钠肽(BNP)水平与缺血的严重程度呈正相关。

关 键 词:急性冠脉综合征  血清肌钙蛋白Ⅰ  血清脑钠肽

Changes of CTNI and BNP Levels in Patients with Acute Coronary Syndrome
Affiliation:ZHANG Huijun, GUO Xichao, GAO Linggen, et al ( Chinese People's Armed Police Force Hospital of Beijing, Beijing 100027, China )
Abstract:Objective: To observe the changes of CTNI and BNP levels and explore its clinical value in patients with acute coronary syndrome(ACS).Method:78 cases of ACS and 40 cases of stable angina pectoris(SAP) were subjected to this study.ACS included acute myocaroal infarction(AMI)and untable angina pectoris(UAP).The serum levels of CTNI and BNP.Result:Levels of serum CTNI and BNP were significantly higher in ACS group than that in SAP group(P〈0.01).Levels of CTNI and BNP were significantly higher in AMI group than in UAP group(P〈0.01).Conclusion: Serum level of CTNI and BNP positively related with degree of myocardial ischemia.
Keywords:Acute coronary syndrome; Cardiac troponin I; B-type natriuretic peptide;
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