新鲜羊膜移植治疗眼表疾病的临床观察

目的 观察新鲜羊膜移植治疗眼表疾病的临床效果。方法 采用新鲜羊膜移植治疗翼状胬肉、复发性翼状胬肉、蚕蚀性角膜溃疡、病毒性角膜溃疡、睑球粘连38例(52眼)，术后随访3～12月。结果 38例术后均未见新鲜羊膜植片急性排斥反应，术后翼状胬肉及角膜溃疡患者在随访期间未见复发，睑球粘连者恢复了眼球的运动功能。结论 新鲜羊膜移植可有效地用于角结膜的重建，充分清除眼表的病变组织和羊膜移植片的缝合固定，对羊膜移植重建眼表功能极其重要。

Fresh amniotic membrane transplantation for ocular surface diseases]

OBJECTIVE: To evaluate the therapeutic effects of fresh amniotic membrane transplantation for ocular surface disorders (OSDs). METHODS: Fresh amniotic membrane transplantation was performed in 38 cases (52 eyes) of ocular surface diseases, including pterygium, recurrent pterygium, Mooren's ulcer, Viral keratitis, and symblepharon. Follow-up studies ranging from 3 to 12 months were conducted. RESULTS: No acute graft rejection was observed following the operation in these cases, and no recurrence was found in cases of pterygium and corneal ulcer during the follow-up period. The ocular movement was restored for the eyes with severe symblepharon. CONCLUSION: Fresh amniotic membrane can be used as a graft material for ocular surface reconstruction, in which complete removal of the pathological tissues and reliable fixation of the amniotic membrane graft are crucial steps.