非肌层浸润性膀胱癌预后因素的研究进展

膀胱癌是泌尿系统最常见的恶性肿瘤之一,移行上皮细胞癌占90%以上,其中超过70%为非肌层浸润性膀胱癌(NMIBC)。大多数NMIBC可经尿道膀胱肿瘤电切术治愈,但术后3～5年内复发率高达60%～90%。术后膀胱灌注治疗虽可以减少疾病的复发与进展,但其作用仍然有限。根据患者不同疾病状态预测膀胱肿瘤的复发与进展,进而选择不同的治疗方法干预具有重要的临床意义。

Research Progress of Prognostic Factors for Non-muscle Invasive Bladder Cancer

Bladder cancer is one of the most common malignant tumors of the urinary tract.Transitional cell carcinoma(TCC)accounts for more than 90%,of which more than 70% are non-muscle invasive bladder cancer(NMIBC).Most of NMIBC can be cured by TURBT,but after 3-5 years the recurrence rate is as high as 60%-90%.Bladder instillation as the treatment can reduce the recurrence and progression of the disease,while its role is still limited.Predicting relapse and progression in patients according to various disease states,and then selecting different approaches of treatment interventions has great clinical significance.