Intra-operative intravenous fluid restriction reduces perioperative red blood cell transfusion in elective cardiac surgery,especially in transfusion-prone patients: a prospective,randomized controlled trial |
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Authors: | George Vretzakis Athina Kleitsaki Konstantinos Stamoulis Metaxia Bareka Stavroula Georgopoulou Menelaos Karanikolas Athanasios Giannoukas |
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Affiliation: | (1) Cardiac Anesthesia Unit, Department of Anesthesiology, University Hospital of Larissa, Greece;(2) Department of Anaesthesiology and Critical Care, University of Patras School of Medicine, Greece;(3) Department of Vascular Surgery, University Hospital of Larissa, Greece |
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Abstract: | Background Cardiac surgery is a major consumer of blood products, and hemodilution increases transfusion requirements during cardiac surgery under CPB. As intraoperative parenteral fluids contribute to hemodilution, we evaluated the hypothesis that intraoperative fluid restriction reduces packed red-cell (PRC) use, especially in transfusion-prone adults undergoing elective cardiac surgery. |
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