脊髓亚急性联合变性MRI影像分析

目的：探讨脊髓亚急性联合变性(SCD)的 MRI 影像特点。方法回顾分析19例 SCD 患者的临床特点及 MRI 资料。结果19例 SCD 中16例出现脊髓异常信号,主要位于颈胸段脊髓背侧,1例累及小脑皮层和延髓；病变为多节段脊髓受累,主要累及脊髓后索或侧索,其中2例累及前索；不同节段脊髓病灶可有不同的形态特征,增强扫描无强化；经维生素 B12治疗后病变范围有不同程度缩小,2例基本消失。结论MRI 对脊髓 SCD 的诊断及疗效监测具有重要价值。

The MRI characteristics of subacute combined degeneration of the spinal cord

Objective To observe the MRI characteristics in subacute combined degeneration (SCD)of the spinal cord.Methods The data of 1 9 SCD patients were retrospectively analyzed by the clinical characteristics and MR images.Results Among the 1 9 pa-tients of SCD,1 6 cases showed abnormal findings.Most of intramedullary lesions located in posterior column of thoracic and cervical spinal cord,and only one case located in cerebellar cortex and medulla oblongata.Lesions were involved in muti-segmental spinal cord,and mainly located in the dorsal or lateral spinal cord,and only two cases located in the anterior spinal cord.Different segmental spinal cord lesions had a different morphological characteristics with no enhancement.After treatments with vitamin B1 2 ,the lesions diminished and even disappeared in 2 cases.Conclusion MRI has important value in the diagnosis and treatment monitor of the SCD.