128层螺旋CT三维重建对OSAHS患者上气道应用价值的研究

目的：评估128层螺旋 CT 上气道三维重建对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者上气道阻塞部位的定位价值。方法采用128层螺旋 CT 对52例确诊的 OSAHS 患者清醒和 Muller 试验下及32例正常人清醒状态下进行上气道容积扫描,分别测量软腭后区、舌后区及会厌后区的气道体积和气道长度,并对各测量指标进行统计学分析。结果与正常对照组相比,清醒状态下 OSAHS 患者上气道长度显著增加(P <0.001)。与清醒状态下相比,OSAHS 患者 Muller 试验下软腭后区气道体积、舌后区气道体积、气道总体积显著减少(P <0.001)。OSAHS 患者上气道长度与平均血氧饱和度(MSaO2)呈负性相关(r=-0.33, P <0.05)。结论128层螺旋 CT 上气道三维重建能较好评估 OSAHS 患者上气道阻塞部位及阻塞的程度,对指导临床治疗有重要意义。

Study of the upper airway in obstructive sleep apnea hypopnea syndrome by 128-slice CT 3D reconstruction

Objective To evaluate the value of 128-slice CT on locating the obstruction site of the upper airway in obstructive sleep apnea hypopnea syndrome (OSAHS)patients by three-dimensional reconstruction technology.Methods There were 52 patients with OSAHS diagnosed by the PSG and 32 cases of healthy volunteers in our hospital.All objects were performed 128-slice CT scan of the upper airway during awake state,and those patients’upper airways were scaned on Muller test.The airway volume of the ret-ropalatal region,retroglottal region and epiglottal region,and the total length of upper airway were measured,and statistical analysis of the each index was obtained.Results During awake state,compared with the control group,the length of upper airway in OSAHS patients increased significantly(P <0.001).Compared with the awake state,OSAHS patients’airway volume of the retropalatal region, retroglottal region and the total airway volume on the Muller test were reduced significantly(P <0.001).OSAHS patients’upper air-way length was correlated negatively to the average MSaO 2 (r=-0.33,P <0.05).Conclusion The three-dimensional reconstruc-tion of upper airway on 128-slice CT can evaluate the position and degree of the obstruction site in OSAHS patients’upper airway better,which has important significance to guide clinical treatment.