前列腺外周带癌T 2 WI影像特征的多因素分析

目的：探讨前列腺外周带癌 T2 WI 影像特征的诊断价值。方法回顾性分析经病理证实的56例外周带前列腺癌的T2 WI图像，另选取75例前列腺增生、7例前列腺炎作为对照组，应用χ2检验对各影像特征进行筛选，再采用多因素Logistic回归分析。结果 T2 WI上病灶的信号强度、形态、均匀度、患侧外周带体积、患侧外周带与移行区分界、前列腺包膜在外周带前列腺癌与对照组的差异均有统计学意义(P<0.05)，病灶的边界、包膜在2组间的差异无统计学意义(P>0.05)。多因素Logistic回归发现影响外周带前列腺癌的危险因素为病灶的形态、患侧外周带体积、前列腺包膜、外周带与移行区分界。结论 T2 WI 上病灶的形态、患侧外周带体积及前列腺包膜是诊断外周带前列腺癌的独立危险因素。

Multivariate Logistic regression analysis for diagnosis of peripheral zone prostate cancer on T2 WI

Objective To evaluate the diagnostic capabilities of T2 WI features in peripheral zone prostate cancer.Methods The characteristics of T2 WI in 56 cases of peripheral zone prostate cancer,75 cases of benign prostatic hyperplasia and 7 cases of prostatitis confirmed by pathology were analyzed retrospectively.Eight indexes were initially screened byχ2 test,then indexes with significant difference were entered into multivariate Logistic regression analysis.Results The indexes showing statistical differences between prostate cancer and benign prostatic disorders were as following:lesion shape,signal intensity,signal uniformity,boundary of peripheral zone and transition zone,the volume of peripheral zone and prostatic capsule on T2 WI (P<0.05).Margin of lesion and capsule between two groups were not statistical differences (P>0.05).By multivariate Logistic analysis,the statistically significant difference were found in lesion shape, the volume of peripheral zone,prostatic capsule and boundary of peripheral zone and transition zone.Conclusion The lesion shape, volume of peripheral zone and prostatic capsule on T2 WI are independent risk factors for peripheral zone prostate cancer.