| 吸烟对血液过氧化与抗氧化平衡的影响 |
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| 引用本文： | 张建华,崔华娟.吸烟对血液过氧化与抗氧化平衡的影响[J].黑龙江医药科学,1998,21(5):27-28. |
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| 作者姓名： | 张建华 崔华娟 |
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| 作者单位： | 佳木斯大学医学院病生教研室，佳木斯大学医学院病生教研室，佳木斯大学医学院病生教研室 |
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| 摘 要： | 比较吸烟与不吸烟人静脉血血浆及红细胞脂质过氧化物-丙二醛（MDA）含量，血浆及红细胞超氧化物歧化酶（SOD）活力、全血谷胱甘肽过氧化物酶（GSH－Px）活力及血浆总抗氧化能力（AOA）．结果表明：吸烟组血浆及红细胞MDA的含量高于不吸烟组（P＜0．01），红细胞SOD含量高于不吸烟组（P＜0．01），血浆SOD、全血GSH－Px活力．血浆AOA均低0于不吸烟组（P＜0．01，P＜0．05，P＜0.05）．提示长期吸烟可使血中氧化与抗氧化失去平衡。
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| 关 键 词： | 红细胞 丙二醛 超氧化物歧化酶 谷胱甘肽过氧化物酶 血浆总抗氧化能力 |
Effects of cigarette smoking on oxidative and antioxidative balance of human blood |
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| Zhang Jianhua,et al.Effects of cigarette smoking on oxidative and antioxidative balance of human blood[J].Heilongjiang Medicine and Pharmacy,1998,21(5):27-28. |
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| Authors: | Zhang Jianhua |
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| Abstract: | The MDA levels in erythrocyte and plasma, the SOD activity in erythrocyte and plasma, the blood GSH-Px activity and the AOA were compared in smokers and non-smokers. It was found that erythrocyte MDA level, plasma MDA and ewtrocyte SOD of smokers were significantly higher than those of the non-smokers (P<0.01). Plasma SOD, blood GSH-Px and plasma AOA of smokers were lower than those of the non-smokers (P<0.01, P<0.05, P<0.05). These results suggest that cigarette smoking might cause an imbalancc between oxidation and antioxidation in blood. |
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| Keywords: | Erythrocyte Malondildehyde (MDA) superocide dismutase(SOD) Glutathione perocidiase (GSH-Px) Antioxide ability (AOA) |
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