首页 | 本学科首页   官方微博 | 高级检索  
     


The prognostic significance of lymph node metastasis and intrapancreatic perineural invasion in pancreatic cancer after curative resection
Authors:Hideo Ozaki  Takehisa Hiraoka  Ryuji Mizumoto  Seiki Matsuno  Yoshiro Matsumoto  Toshimichi Nakayama  Tsukasa Tsunoda  Takashi Suzuki  Morito Monden  Yoichi Saitoh  Hidemi Yamauchi  Yoshiro Ogata
Affiliation:(1) Department of Surgery, National Cancer Center Hospital, 1-1 Tsukiji 5-Chome, Chuo-ku, Tokyo 104, Japan, JP;(2) First Department of Surgery, Kumamoto University School of Medicine, 1-1-1 Honjo, Kumamoto 860, Japan, JP;(3) First Department of Surgery, Mie University Faculty of Medicine, 2-174 Edobashi, Tsu 514, Japan, JP;(4) First Department of Surgery, Tohoku University School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980, Japan, JP;(5) First Department of Surgery, Yamanashi Medical University, 1110 Tamaho, Yamanashi 409-38, Japan, JP;(6) Second Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830, Japan, JP;(7) Second Department of Surgery, Nagasaki University School of Medicine, 7-1 Sakamoto-machi, Nagasaki 852, Japan, JP;(8) Second Department of Surgery, Yamaguchi University School of Medicine, 1144 Kogushi, Nishi-ku, Ube 755, Japan, JP;(9) Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita 565, Japan, JP;(10) First Department of Surgery, Kobe University School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650, Japan, JP;(11) Department of Surgery, Sendai National Hospital, 2-8-8 Miyagino, Miyagino-ku, Sendai 983, Japan, JP;(12) Department of Surgery, Tochigi Cancer Center, 4-9-13 Yonan, Utsunomiya 320, Japan, JP
Abstract:P < 0.02). In the group of patients with nodal metastasis, the 5-year survival rate for those without perineural invasion was 17%, while that for those with perineural invasion was 10%. The most favorable 5-year survival of 89% was observed in the subgroup of patients with stage I disease without perineural invasion. Thus, pancreatic adenocarcinoma categorized by the combination of these independent types of biological behavior showed 5-year survival rates ranging from very high to low, indicating that these two factors play an important role in the prognosis of this disease. (Received for publication on July 18, 1997; accepted on May 15, 1998)
Keywords:: pancreatic adenocarcinoma  pancreatectomy  prognostic factor  lymph node metastasis  perineural invasion
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号