| 舒督丸提取工艺研究 |
| |
| 引用本文： | 刘雅敏,李振国,张黎莉,詹云静. 舒督丸提取工艺研究[J]. 时珍国医国药, 2007, 18(6): 1450-1451 |
| |
| 作者姓名： | 刘雅敏 李振国 张黎莉 詹云静 |
| |
| 作者单位： | 1. 河南中医学院,河南,郑州,450008
2. 河南省药品检验所,河南,郑州,450008 |
| |
| 摘 要： | 目的优选研究舒督丸的提取溶剂和提取工艺条件。方法用小鼠醋酸扭体法比较方剂水提物、乙醇提物的镇痛作用强度,优选提取溶剂;以柚皮苷提取率和水总浸出物提取率为评价指标,对提取工艺进行正交试验,优选合理的提取工艺参数。结果以水为提取溶剂其镇痛作用最显著。最佳提取工艺条件是提取4次,每次提取时间分别为3,2,1,1 h,每次加水量分别为6,4,4,2倍。结论确定的提取工艺条件能使有效成分被充分提取,保证药效与制剂质量。
|
| 关 键 词： | 舒督丸 提取溶剂 提取工艺 柚皮苷 |
| 文章编号： | 1008-0805（2007）06-1450-02 |
| 收稿时间： | 2006-11-28 |
| 修稿时间： | 2006-11-282007-02-28 |
Studies on the Extraction Process of ShuDu Pill |
| |
| LIU Ya-min,LI Zhen-guo,ZHANG Li-li,ZHAN Yun-jing. Studies on the Extraction Process of ShuDu Pill[J]. Lishizhen Medicine and Materia Medica Research, 2007, 18(6): 1450-1451 |
| |
| Authors: | LIU Ya-min LI Zhen-guo ZHANG Li-li ZHAN Yun-jing |
| |
| Affiliation: | 1. Henan Traditional Chinese Medical College , Zhengzhou 450008, China ; 2. Henan Institute for Drug Con trol, Zhengzhou 450008, China |
| |
| Abstract: | Objective To select the extraction solvent and conditions of ShuDu Pill.Methods Acetic acid writhing method on mice was used to compare the analgesic effects of the water extract and the alcohol extract orthogonal design was used to optimize the reasonable extraction conditions with the evaluation markers such as naringin extraction rate and water extract.Results The analgesic effect treated with the water extract is more significant.The extraction conditions were as follows:the medical material was soaked in 6,4,4,2 times water and boiled 4 times,3,2,1,1 hours for each time.Conclusion The extraction conditions established can make the extraction rate of active components high and make the therapy and quality optimal. |
| |
| Keywords: | Shu Du Pill The extraction solvent The extraction process Naringin |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
