医院重症监护病房77株鲍曼不动杆菌临床耐药性分析

目的 了解医院临床分离的鲍曼不动杆菌临床感染、耐药情况.方法 收集都江堰市人民医院2010年至2011年重症监护病房临床标本,进行细菌培养鉴定及药物敏感性试验回顾性分析.结果 共分离鲍曼不动杆菌77株,耐药菌73株,痰标本分离率最高(80.52％),其次是分泌物和尿液.该菌对左氧氟沙星的耐药率2010年为46.75％,2011年为50.53％；对亚胺培南的耐药率2010年为46.20％,2011年为52.80％.菌株耐药率有逐年上升趋势.结论 鲍曼不动杆菌在重症监护病房常见,对抗菌药物的耐药率高,且多重耐药.应合理使用抗菌药物,减少多重耐药菌株的产生.

Drug Resistance of Acinetobacter Baumannii in ICU of Our Hospital

Objective To understand the drug resistance situation of clinical infection of clinically isolated Acinetobacter baumannii. Methods The clinical specimens from ICU of our hospital from 2010 to 2011 were collected for conducting the bacterial culture iden- tification and the drug susceptibility retrospective analysis. Results Seventy- seven strains of Acinetobacter baumannii and 73 strains of resistant bacteria were isolated during these 2 years. The sputum specimens had the highest isolation rate, accounting for 80. 5%, followed by the secretion and urine specimens. The resistance rate to levofloxacin was increased from 46.75% in 2010 to 50.53% in 2011; the resistance rate to imipenem and was 46. 20% in 2010 and 52. 80% in 2011 respectively. The drug resistance rate of bacterial strains increased year by year. Conclusion Acinetobacter baumannii is common in ICU ward and has high resistance rate to antibacterial drugs. Antimicrobial agents should be rationally used for reducing the generation of multiple drug- resistant strains.