匹伐他汀治疗高胆固醇血症36例的临床疗效分析

目的 探讨匹伐他汀治疗高胆固醇血症的临床疗效.方法 将68例高胆固醇血症患者按盲目随机法分为两组,观察组36例使用匹伐他汀,对照组32例使用辛伐他汀.治疗结束后,将总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)、高密度蛋白胆固醇(HDL-C)水平进行对比.结果 两组TC与LDL-C降低程度与治疗前相比均有明显差异(P＜0.05),TG与HDL-C均无明显差异(P＞0.05).两组患者LDL-C水平的达标率与不良反应发生率均无明显差异(P＞0.05).结论 匹伐他汀治疗高胆固醇血症疗效显著,能有效降低TC及LDL-C水平,不良反应率低,安全水平高,值得临床推广.

Clinical Efficacy of Pitavastatin in Treating Hypercholesterolemia in 36 Cases

Objective To investigate the efficacy of pitavastatin in treating hypercholesterolemia. Methods Sixty- eight patients with hypercholesterolemia were randomly divided into the two groups by the blind random method. The observation group（36 cases） recieved pitavastatin while the control group（32 cases） received simvastatin. After treatment, the total cholesterol（TC）, low density lipoprotein cholesterol （ LDL - C ）, triglycerides （TG）, high - density lipoprotein cholesterol（ HDL - C ） were compared between the two groups. Results After treatment the decrease degree of TC and LDL- C in the two groups had statistical differences（ P 〈 0. 05 ）. but TG and HDL-C had no statistical differences（P 〉 0. 05）. The reaching standard rate of the LDL-C levels and the occurrence rates of adverse reactions in the two groups had no statistical differences（ P 〉 0. 05）. Conclusion Pitavastatin has significant effect in treating hypercholesterolemia,can effectively reduce the TC,LDL-C levels,with low occurrence rate of adverse reactions and high safety and is worthy of promotion.