| 甘草酸的利胆和对平滑肌的作用研究 |
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| 引用本文： | 黄能慧,李诚秀,夏炳南. 甘草酸的利胆和对平滑肌的作用研究[J]. 贵阳医学院学报, 1988, 0(2) |
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| 作者姓名： | 黄能慧 李诚秀 夏炳南 |
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| 作者单位： | 贵阳医学院药理学教研室，贵阳医学院药理学教研室，贵阳医学院药理学教研室 |
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| 摘 要： | 本文实验表明甘草酸、甘草酸胺能增加正常大鼠以及用四氯化碳损伤肝脏大鼠的胆汁分泌,三小时总胆汁分泌量分别是对照组的2.5及2倍。甘草酸及甘草酸胺也能促进小鼠胆汁分泌。另外,甘草酸胺对兔离体肠肌有松弛作用,并能对抗 Ach 引起的平滑肌收缩反应。
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| 关 键 词： | 甘草次酸 利胆剂和胆汁分泌促进剂 胆硷酯酶抑制剂 胆汁 平滑肌 |
EXPERIMENTAL STUDIES ON THE EFFECT OF GLYCYRRHETIC ACID ON CHOLERESIS AND SMOOTH MUSCLES |
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| Huang Nenghui. EXPERIMENTAL STUDIES ON THE EFFECT OF GLYCYRRHETIC ACID ON CHOLERESIS AND SMOOTH MUSCLES[J]. Journal of Guiyang Medical College, 1988, 0(2) |
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| Authors: | Huang Nenghui |
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| Affiliation: | Huang Nenghui,Department of Pharmacology |
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| Abstract: | Our experiments indicate that glycyrrhetic acid and monoammonium glycy- rrhetate could increase bile excretion in normal rats and in rats with liver injury.The total amount of bile excretion for 3 hours was twice as much as controls.They also increased bile excretion in mice.In addition.monoam- monium glycyrrhetate was found to be able to relax the isolated intestinal smooth muscles of rabbits and antagonize constraction of the Smooth muscles induced by acetylcholine. |
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| Keywords: | Glycyrrhetinic acid Cholagogues and choleretics Cholinesterase inhibitors Bile Smooth muscles |
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