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重症急性胰腺炎血液稀释治疗犬的实验观察
引用本文:戴荣,许琳,陈梅树,陈宏志,徐江英,吴秀莲,王吉甫. 重症急性胰腺炎血液稀释治疗犬的实验观察[J]. 南京军医学院学报, 1995, 0(1)
作者姓名:戴荣  许琳  陈梅树  陈宏志  徐江英  吴秀莲  王吉甫
作者单位:海军医学高等专科学校外科教研室 南京210099(戴荣,许琳,陈梅树,陈宏志,徐江英,吴秀莲),中山医科大学附属第一医院胃肠外科 广州510080(王吉甫)
摘    要:本实验提示:患重症急性胰腺炎(SAP)时,在外科手术的前提下,及早经胰腺局部动脉灌注血管扩张剂和抑酶剂,尤其是用低分子右旋糖酐作为扩容剂,比单纯的晶体扩容复苏更为重要,通过改变其血流,增加胰腺的灌注,从而防止SAP早期局部缺血所至的继发性损伤.

关 键 词:重症急性胰腺炎  动物模型  低分子右旋糖酐  血液稀释

Hemadilution on Experimental Severe Acute Pancreatitis in Dogs
Dai Rong,Xu Lin,Chen Meishu,Chen Hongzhi,Xu Jiangying,Wu Xiulian. Hemadilution on Experimental Severe Acute Pancreatitis in Dogs[J]. Journal of Nanjing Military Medical College, 1995, 0(1)
Authors:Dai Rong  Xu Lin  Chen Meishu  Chen Hongzhi  Xu Jiangying  Wu Xiulian
Abstract:We consider that under the surgical presupposition, vasodilatation prepara-tions and trypsin inhibitors were early perfused into pancreatic arteries,especially partial re-placement of blood by dextran of low molecule preparations,the result of which has shown increase in pancreatic perfusion by improving blood fluidith. In conjunction with means,a new and effective method of dextran therapy may protect the pancreas from the secondary in-jury due to the early ischaemic phase of severe acute pancreatitis(SAP). The experimental ev-idence suggests that pancreatic ischaemia in the early phase of SAP be important in the devel-opment of pancreatic necrosis.
Keywords:severe acute pancreatitis  animal model  dextran of low molecule  hemadilu-tion
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