| 抗体芯片技术研究进展 |
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| 引用本文： | 赵玉辉,贾智艳,包红梅. 抗体芯片技术研究进展[J]. 国际免疫学杂志, 2009, 33(6): 196-199. DOI: 10.3760/cma.j.issn.1673-4394.2010.03.009 |
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| 作者姓名： | 赵玉辉 贾智艳 包红梅 |
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| 作者单位： | 中国农业科学院哈尔滨兽医研究所,哈尔滨,150000;哈尔滨医科大学附属第一医院,150001; |
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| 摘 要： | 抗体芯片是蛋白质组学的新兴技术,属于蛋白芯片的一个分支,具有高通量、高特异性、平行性分析的优点.目前抗体芯片技术在癌症标记物发现、药物发展、毒素检测、细胞因子研究、信号转导、表达产物分析、RNAs检测以及其它的基础和应用蛋白质组学研究等领域具有广泛的应用,并且在临床上有补充或取代传统免疫学方法的趋势.
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| 关 键 词： | 抗体芯片 载体包被 样品标记 检测 数据处理 |
Advances in antibody microarray technologies |
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| ZHAO Yu-hui,JIA Zhi-yan,BAO Hong-mei. Advances in antibody microarray technologies[J]. International Journal of Immunology, 2009, 33(6): 196-199. DOI: 10.3760/cma.j.issn.1673-4394.2010.03.009 |
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| Authors: | ZHAO Yu-hui JIA Zhi-yan BAO Hong-mei |
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| Abstract: | Antibody microarray, as a branch of protein microarray, is one emerging class of proteomic technologies with high-throughput, parallelizing, and high specificity. Antibody microarrays hold great promise as a valuable tool for evaluation of novel biomarkers in disease, drug development, toxins detection, signal translation, cytokine research, protein expression production analysis, RNA detection, basic and applied pro-teomics research,etc. Autibody microarry may be a substitution of conventional immunoassays. |
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| Keywords: | Antibody microarraySubstrate modificationSample labelingDetectionData processing |
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