电针“内关”对心肌缺血所致兔胸髓背角神经元电活动反应的影响

在乌拉坦-氯醛糖麻醉兔上，用玻璃微电极细胞记录外背角神经元电活动，观察了胸髓（T2-T3）背角在整合电体“内关”和急性心肌缺血（AMI）信息中的作用。结果为：①AMI后，83个背角神经元中，18个放电频率明显增加，14个明显减少，其余51个没明显变化；②AMI引起兴奋反应的10个神经元中，电针“内关”后，有9个被抑制，1个仍呈兴奋状态；AMI引起抑制反应的8个神经元中，电针“内关”后有7个被解除抑制，另1个仍维持抑制状态；③检查了83个背角神经元的感受野及其反应的生理学类型。结果表明，电针“内关”与AMI的信息可在胸髓背角发生会聚性反应，背角参与电针“内关”与AMI的整合过程，因而亦是内关-心脏联系的环节之一。

Influence of Electroacupuncture of Neiguan(PC 6) on Ami-induced Changes in Electrical Activity of Dh neurons

The electrical activity of the dorsal horn (DH) neurons was recorded extracellularly by glass micro-pipettes in urethane-chloralose anesthetized rabbits to analyze the role of the thoracic segments (T2-T3) of the spinal cord in the integration of information from electroacupuncture (EA) at Neiguan (PC 6) and acute myocardial ischemia(AMI). Results were: 1) after AMI, of 83 DH neurons, 18 displayed a significant excitatory response, 14 an obvious inhibitory reaction and 51 no apparent change; 2) after EA at Neiguan (PC 6), of 10 neurons with AMI-induced excitatory response, the electrical activity of 9 neurons was suppressed and the other 1 still maintained its excitatory state;of 8 neurons with AMI-induced inhibitory response, 7 were relieved from the suppressed state, the other 1 had no change following EA; and 3) the receptive field and the responsive types to somatic stimulation were examined in 83 DH neurons. Results showed that signals from EA at Neiguan (PC 6) and AMI could converge to the DH neurons of T2 -T3. It suggests that DH participates in the integrative course of information from EA and AMI and thus it is one of the connective links betwen Neiguan(PC 6) and the heart