天王补心丹加减治疗习惯性便秘伴失眠的临床疗效观察

目的：观察天王补心丹组方加减对习惯性便秘伴失眠患者的临床疗效。方法：将63例符合诊断患者随机分为两组。治疗组32例以天王补心丹汤剂加减治疗；对照组31例口服西沙必利（20mg/次，2次/d）及脑益嗪片（25mg/d，睡前服）治疗。疗程均为30d，随访3个月，观察患者便秘及失眠缓解情况，并记录其副作用。结果：治疗组有效率达93.75%，对照组为74.1%，两组比较有显著差异（P<0.05）。结论：天王补心丹组方加减治疗习惯性便秘伴失眠有肯定的临床疗效。

Clinical observation of Tianwang Buxin pill on treating habitual constipation following with insomnia

Objective： To observe the clinical effect of Tianwang Buxin pill on treating Habitual constipation following with insomnia. Methods： 63 cases were randomly divided into 2 groups, 32 cases were treated with the Tianwang Baoxin pill in the treatment group, 31 cases were given cisapride （20mg/time, 2 times/day） and stutgeron tablet （25mg/day, taken at bed-time） orally in the control group. Treatment durations for both groups are 30 days and we followed the cases for three month and observed the remission rates of constipation and insomnia and the side-effects. Results： The efficiency rate was 93.7% in the treatment group, another was74.1%, there was a significant difference （P〈0.05）. Conclusion： There is a positive treatment effect of Tianwang Buxin pill in treating habitual constipation and insomnia. With few side-effects and little medicine dependence, it is worthy for clinical extending.