Oxygen tension distributions in the cornea: a re-examination |
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Authors: | I Fatt R D Freeman D Lin |
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Affiliation: | 1. School of Optometry, University of California, Berkeley, Calif. 94720, U.S.A.;2. Department of Mechnical Engineering, University of California, Berkeley, Calif. 94720, U.S.A. |
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Abstract: | Previous calculations of the steady-state oxygen distribution in the in vivo cornea were made using assumed values for the needed parameters. Recent work has yielded experimental results on these quantities and we have used these to compute the oxygen tension distributions in the cornea for several conditions. The main result, which differs from the earlier calculations, is that there is an oxygen flux from the aqueous into the cornea in the open-eye steady-state condition. Oxygen tension profiles are also presented for the closed eye and for a corneal-contact lens system. Implications of the various profiles are discussed. |
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