| 碳酸锂合并^131I治疗Graves病的临床药理作用 |
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| 引用本文： | 吴红 邓敬兰. 碳酸锂合并^131I治疗Graves病的临床药理作用[J]. 医学争鸣, 1992, 13(1): 66-68 |
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| 作者姓名： | 吴红 邓敬兰 |
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| 作者单位： | 西京医院核医学科(吴红)，西京医院核医学科(邓敬兰) |
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| 摘 要： |
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| 关 键 词： | 碘－131 碳酸锂 甲状腺肿 |
Clinical pharmacological efficiency of lithium carbonate combined with ~131I in treatment of Graves disease |
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| WU Hong and DENG Jing-Lan. Clinical pharmacological efficiency of lithium carbonate combined with ~131I in treatment of Graves disease[J]. Negative, 1992, 13(1): 66-68 |
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| Authors: | WU Hong and DENG Jing-Lan |
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| Affiliation: | WU Hong and DENG Jing-Lan Department of Nuclear Medicine,Xijing Hospital |
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| Abstract: | In order to evaluate therapeutic effects of different doses of lithium carbonate (Li2CO3) combined with (?)I in treatment of Graves disease, 17 patients were investigated. Results showed that TT3 and TT4 in serum in 7-14 days after taking 500 mg/d or 625 mg/d of Li2CO3 were significantly lower than that of before therapy. No evidence of increasing of TgAb and TmAb level in serum and goiter were found. Perchlorate discharge test was undertaken after giving the two doses of Li2CO3 to the patients and the discharge rates were all lower than 5%, which indicates that Li does not aflect the organization of 131I in thyroid. Proteinuria was observed in some patients in short time (3-7 days) after giving 625 mg/d of Li2CO3, which indicates that higher dose of Li2CO3 has no advantage in treatment of Graves disease. |
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| Keywords: | Graves disease iodine-131 lithium carbonate therapeutics |
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