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药敏试验后抗菌药物的选择分析
引用本文:张骞峰,孙增先,孙晓,徐丙超.药敏试验后抗菌药物的选择分析[J].抗感染药学,2009,6(1):40-42.
作者姓名:张骞峰  孙增先  孙晓  徐丙超
作者单位:江苏省连云港市第一人民医院,江苏,连云港,222002
基金项目:江苏省药师协会默沙东基金 
摘    要:目的:分析临床上药敏试验(drug sensitivity test,DST)后抗菌药物选择的合理性。方法:回顾性调查180例细菌培养阳性的患者病历,分析抗菌药物在DST后的应用情况。结果:180例细菌培养阳性结果,革兰阳性细菌为52例,革兰阴性菌为140例。医师在DST后调整抗菌药物95例,未调整85例。DST后抗菌药物再选择的主要不合理性为:未完全掌握抗菌谱,不熟悉药物的药动学、药效学,不了解细菌的天然性和获得性耐药,不降级应用抗菌药物。结论:在DST后临床上抗菌药物的选择存在5种不合理现象。

关 键 词:药敏试验  抗菌药物  选择

Analysis of Antibiotics Choice after Drug Sensitivity Tests
ZHANG Qian-feng,SUN Zeng-xian,SUN Xiao,XU Bing-chao.Analysis of Antibiotics Choice after Drug Sensitivity Tests[J].Anti-infection Pharmacy,2009,6(1):40-42.
Authors:ZHANG Qian-feng  SUN Zeng-xian  SUN Xiao  XU Bing-chao
Institution:(Lianyungang No. 1 People's Hospital of Jiangsu Province, Lianyungang Jiangsu 222002, China)
Abstract:Objective: To analyse the antibiotics choice after drug sensitivity tests. Methods: Retrospective survey of 180 patients with medical records positive to bacilliculture, and analysis of antibiotics choice. Results: Among 180 cases, gram-negative bacteria were 52 strains, and gram-positive 140 strains. Ninety-five cases were adjusted, and 85 cases were not adjusted. The main unreasonable choices were: not to be familiar with antibacterial spectrum, PK, PD, natural and acquired drug resistance, and not to have suitable application of antibiotics. Conclusion: There are five unreasonable choices after drug sensitivity tests.
Keywords:drug sensitivity tests  antibiotics  choice
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