能谱CT标准化碘密度在结直肠癌分级鉴别诊断中的价值

目的:评价能谱C T成像在结直肠癌动脉期(A P)、门脉期(P P)定量碘密度测量中的诊断价值.方法:依据病理结果,将2018年8月—2020年8月的威海市中心医院30例结直肠癌患者分为两组:一组为低级别组,包括高、中度分化癌(n=21),另一组为高级别组,包括低分化癌(n=9).病灶碘密度(ID)由碘物质分解图像得到...

The value of spectral CT normalized iodine density in the differential diagnosis of colorectal cancer with different pathological grade

Objective To evaluate the diagnostic value of spectral CT imaging in the quantitative iodine density measurement of the arterial phase(AP)and portal phase(PP)of colorectal cancer.Methods According to the pathological results,30 patients with colorectal cancer were divided into two groups:one group was a low-grade group,including high and moderately differentiated cancers(n=21),and the other group was a high-grade group,including poorly differentiated cancers(n=9).The iodine density(ID)was obtained from the iodin-based material decomposition image,and standardized processing(taking the abdominal aorta or iliac artery iodine density at the same level as a reference)to obtain the normalized iodine density(NID).Analyze the difference of ID and NID between AP and PP.Results In the low-grade group,the ID value of AP was 15.43±2.7100μg/cm3,the NID value was 0.17±0.05,the ID value of the PP was 18.92±2.54100μg/cm3,and the NID value was 0.62±0.11.In the high-grade group,the ID value of the AP was 15.60±1.46100μg/cm3,the NID value was 0.15±0.01,the ID value of the PP was 18.09±1.67100μg/cm3,and the NID value was 0.43±0.06.the NID of the AP and the NID of the PP are significantly different(P<0.05).Use SPSS 22 to do ROC curve analysis:When the NID is 0.5015 in the portal phase(PP),the sensitivity to distinguish low-grade and high-grade is 85.7%,and the specificity is 88.9%.Conclusion One,The normalized iodine density(NID)in the arterial phase(AP)and portal phase(PP)can distinguish low-grade and high-grade colorectal cancer.Two,The normalized iodine density(NID)in the portal phase(PP)has the greatest diagnostic value.