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枸橼酸咖啡因对早产儿呼吸暂停的影响观察
作者姓名:张华  魏春雪  赵巧玲
作者单位:内蒙古自治区呼伦贝尔市人民医院新生儿科;内蒙古民族大学呼伦贝尔临床医学院
摘    要:目的 观察枸橼酸咖啡因对早产儿呼吸暂停(apnea of prematuritye,AOP)的影响.方法 将2017年11月—2020年2月本院住院的84例AOP患儿随机分为试验组和对照组,各42例,两组均接受经鼻持续气道通气治疗,对照组另加氨茶碱治疗,试验组另加枸橼酸咖啡因治疗;比较两组早期肺功能参数(每分钟通气量、...

关 键 词:早产儿  呼吸暂停  枸橼酸咖啡因  氨茶碱  经鼻持续气道正压通气  疗效

Effect of Caffeine Citrate on Apnea of Prematuritye
Authors:ZHANG Hua  WEI Chunxue  ZHAO Qiaoling
Institution:(Department of Neonatology,Hulunbeir People's Hospital,Hulunbeir Inner Mongolia 021008,China;Hulunbeir Clinical School,Inner Mongolia University of Nationalities,Hulunbeir Inner Mongolia 021008,China)
Abstract:Objective To observe the effect of caffeine citrate on apnea of prematuritye(AOP).Methods From November 2017 to February 2020,84 infants with AOP in our hospital were randomly divided into two groups:the experimental group and the control group,42 cases in each group.Both groups were treated with nasal-continuous positive airway pressure,the control group was treated with aminophylline,and the experimental group was treated with caffeine citrate;the early lung function parameters(ventilation per minute,tidal volume,peak time ratio,peak volume)of the two groups and clinical efficacy was comapred.Results After treatment,the early lung function parameters and clinical effect in the experimental group were significantly higher than those in the control group(P<0.05).Conclusion Caffeine citrate can improve the lung function and clinical symptoms of AOP infants significantly.
Keywords:preterm infants  apnea  caffeine citrate  aminophylline  nasalcontinuous positive airway pressure  efficacy
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