多巴胺对感染性休克患者IL-8、CRP水平的影响

目的探究多巴胺治疗感染性休克患者的临床效果。方法将50例感染性休克患者以单双号编号法随机分为试验组(25例,常规治疗+多巴胺)和对照组(25例,常规治疗)。比较两组的治疗效果。结果试验组的治疗总有效率高于对照组(P<0.05)。治疗后,两组WBC、APACHEⅡ评分、RR、HR、动脉血乳酸、PCT、TNF-α、CRP、IL-8、IL-6水平均低于治疗前,SBP高于治疗前,且试验组优于对照组(P<0.05)。试验组并发症总发生率低于对照组(P<0.05)。结论多巴胺治疗感染性休克患者的效果显著,能降低炎性因子水平以及并发症发生率,改善患者的血压、RR、HR、动脉血乳酸等指标水平。

Effects of dopamine on IL-8 and CRP levels in patients with septic shock

Objective To investigate the clinical effect of dopamine in the treatment of patients with septic shock.Methods Fifty patients with septic shock were randomly divided into experimental group(25 cases,routine treatment+dopamine)and control group(25 cases,routine treatment)by odd-even numbering method.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment of the experimental group was higher than that of the control group(P<0.05).After treatment,WBC,APACHEⅡscore,RR,HR,the levels of arterial blood lactic acid,PCT,TNF-α,CRP,IL-8 and IL-6 of the two groups were lower than those before treatment,SBP was higher than that before treatment,and those in the experimental group were better than the control group(P<0.05).The total incidence of complications in the experimental group was lower than that in the control group(P<0.05).Conclusion The dopamine in the treatment of patients with septic shock has a significant effect,it can reduce the levels of inflammatory factors and incidence of complications,improve the patients'blood pressure,RR,HR,arterial blood lactate and other indexes levels.