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艾地苯醌联合尼莫地平应用于血管性痴呆的临床疗效
作者姓名:邢春丽  闫桂珍  崔晨
作者单位:济南市历下区人民医院神经内科
摘    要:目的 观察艾地苯醌与尼莫地平联合应用于血管性痴呆治疗的临床效果.方法 选取2018年6月—2019年8月在我院接受治疗的76例血管性痴呆患者为研究对象,采用随机数字表法分为试验组(n=38)和对照组(n=38).对照组采用尼莫地平治疗,试验组在对照组的基础上加用艾地苯醌.两组治疗3个月后,采用简易智力状态评定量表(Mi...

关 键 词:艾地苯醌  尼莫地平  血管性痴呆  MMSE评分  MoCA评分  ADL评分

Clinical Effect of Idebenone Combined With Nimodipine on Vascular Dementia
Authors:XING Chunli  YAN Guizhen  CUI Chen
Institution:(Department of Neurology,Lixia District People's Hospital,Ji’nan Shandong 250014,China)
Abstract:Objective To observe the clinical effect of combination of idebenone and nimodipine in the treatment of vascular dementia.Methods 76 patients with vascular dementia who were treated in our hospital from June 2018 to August 2019 were selected as the research objects and randomly divided into experimental group(n=38)and control group(n=38).The control group was treated with nimodipine,The experimental group was treated with idebenone tablet.After 3 months of treatment,MMSE,MoCA and ADL were used to evaluate the results of treatment.Results After treatment,MMSE score,MoCA score and ADL score of the two groups were significantly increased,and the increase of the experimental group was significantly better than that of the control group,the above differences were statistically significant(P<0.05).Conclusion The combination of idebenone and nimodipine in the treatment of vascular dementia can effectively improve the cognitive function,language function and behavior function of patients,with good clinical effect.
Keywords:idebenone  nimodipine  vascular dementia  MMSE  MoCA  ADL
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