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小单孢菌M-90诱变方法的研究
引用本文:王耀伟,王鲁燕,王骋.小单孢菌M-90诱变方法的研究[J].中国药科大学学报,1994(5).
作者姓名:王耀伟  王鲁燕  王骋
作者单位:中国药科大学抗生素研究室
摘    要:以高温、LiCl、LiCl+UV、甲胺+UV、吖啶橙等理化诱变剂对玫瑰降红色小单孢菌M-90进行诱变育种。高温、LiCl+UV、甲胺+UV、吖啶橙处理后都得到了高产菌株。其中以高温、LiCl+UV效果最好。经过复筛与传代,得到了具有遗传稳定性的高产菌株,且发酵液中非活性组分较出发菌株减少。

关 键 词:小单孢菌  诱变育种  诱变剂

Study on the Mutation Micromonospora M-90
wang Yaowei,wang Luyan,wang Cheng.Study on the Mutation Micromonospora M-90[J].Journal of China Pharmaceutical University,1994(5).
Authors:wang Yaowei  wang Luyan  wang Cheng
Abstract:This paper reported mutation breeding of Micromonospora roseorubra M-90 with high-temperature,LiCl,LiCl UV,methylamine UV and acriding orange.The results showed that high-yielding mutants were obtained by the treatments or all these mutagens.It was found that high-temperature and LiCl UV were the better mutagens than the others.After rescreening and reproductions,it is indicated that these high-yielding mutants have inheritable stability and the inactive components are reduced compared with the NS strain.
Keywords:Micromonospora  Mutation breeding  Mutagens
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