PTCA术后再狭窄机制的研究进展

冠状动脉狭窄 ,除常规应用扩冠药物外 ,近代已开展经皮冠状动脉球囊扩张置放支架疗法 (PTCA) ,使临床疗效明显提高。但仍有部分病例接受PTCA后发生再狭窄的可能。较详细概述了PTCA后再狭窄的机制 ,发生的时间 ,产生的相关因素及再狭窄的病理过程。同时 ,对基质金属蛋白酶和纤溶酶系统与再狭窄的关系也进行探讨

Research Progress of Pathogenesis of re-stenosis after PTCA Operation

The coronary artery stenosis is treated with balloon angioplasty and stent (PTCA) to improve the curative effect in clinic recently besides the routine therapy with dilated coronary artery drug. But there are partial patients who have the possibility of re-stenosis. This paper had discussed about coronary artery stenosis in the mechanism, happening time, correlative factors and pathogenesis. The relationship between matrix metallo proteinase, fibrinolysin system and re-stenosis of coronary artery were also investigated.