| 生长抑素受体1～5与消化系统疾病关系的研究进展 |
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| 引用本文： | 郭佳念,钟英强. 生长抑素受体1～5与消化系统疾病关系的研究进展[J]. 国外医学:内科学分册, 2008, 35(4): 218-222 |
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| 作者姓名： | 郭佳念 钟英强 |
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| 作者单位： | 中山大学附属第二医院消化内科 广东广州510182 |
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| 摘 要： | 生长抑素受体(SSTR)作为与生长抑素(SST)及其类似物特异性结合的受体在体内广泛分布,尤其是消化系统。SST发挥生理作用需要与其受体结合。SSTR主要有5种亚型(即SSTR1～5),在不同的种属和组织中分布与表达的亚型及量均不同。研究表明,SSTR在相关疾病的诊断与治疗中起重要作用。本文就SSTR各亚型在消化系统疾病中的分布特点及其与相关疾病的关系进行综述。
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| 关 键 词： | 生长抑素 生长抑素受体 消化系统疾病 |
Research progess in the relationship between somotostatin receptor 1～5 and digestive system diseases |
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| Gun Jia-nian,ZHONG Ying-qiang. Research progess in the relationship between somotostatin receptor 1～5 and digestive system diseases[J]. Foreign Medical Sciences(Section of Internal Medicine), 2008, 35(4): 218-222 |
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| Authors: | Gun Jia-nian ZHONG Ying-qiang |
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| Abstract: | Somotostatin receptor(SSTR)is a kind of receptors bound by somatostatin(SST)and its analogues(SSA)specially,which is distributed widely in every part of the human body,especially the digestive system.Binding to its receptors,SST exerts many physiological functions.There are 5 SSTR subtypes(SSTR1~5),and they are expressed differently in disparate species and tissues.Many researches demonstrated that SSTR plays an important part in the diagnosis and therapy of many associated diseases.This paper reviews the distribution characteristics of SSTR and the relationship between SSTR and digestive diseases. |
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| Keywords: | Somatostatin(SST) Somotostatin receptor(SSTR) Digestive system diseases |
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