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Characterizing adolescents with heavy menstrual bleeding and generalized joint hypermobility
Authors:Nicole E. Kendel  Fareeda W. Haamid  Myra Christian‐Rancy  Sarah H. O'Brien
Abstract:Patients with generalized joint hypermobility (JHM) may experience excessive bruising/bleeding, with heavy menstrual bleeding (HMB) commonly reported. We performed a retrospective review of 30 adolescents seen in a Young Women's Hematology Clinic with both HMB and JHM. We found that (1) a significant delay (mean 36 months, range 5–72) occurred between menarche and referral to specialty care, (2) HMB had moderate to severe impact on school and physical activities in 60% of patients, and (3) most patients (68%) required escalation of their initial therapy. We suggest providers consider JHM as a risk factor for a more complex clinical course.
Keywords:adolescent  bleeding disorders other than hemophilia  Ehlers–  Danlos syndrome  menorrhagia
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