| 药动学-药效学结合模型的研究进展 |
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| 引用本文： | 赵刚,田长青,李静. 药动学-药效学结合模型的研究进展[J]. 中国临床药理学与治疗学, 2005, 10(4): 361-366 |
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| 作者姓名： | 赵刚 田长青 李静 |
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| 作者单位： | 山东省医学科学院药物研究所,济南,250062,山东 |
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| 摘 要： | 本主要对近年来药动学．药效学结合模型在模型建立、药理学、毒理学、临床应用及新药研发等方面的进展进行了综述，并展望其发展前景。
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| 关 键 词： | 药动学 药效学 药动学 -药效学模型 临床 试验 |
| 文章编号： | 1009-2501(2005)04-0361-06 |
| 修稿时间： | 2005-02-05 |
Research advances of pharmacokinetic-pharmacodynamic model |
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| ZHAO Gang,TIAN Chang-qing,LI Jing. Research advances of pharmacokinetic-pharmacodynamic model[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2005, 10(4): 361-366 |
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| Authors: | ZHAO Gang TIAN Chang-qing LI Jing |
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| Affiliation: | ZHAO Gang,TIAN Chang-qing,LI Jing Institute of Materia Medica,Shandong Academy of Medical Science,Jinan 250062,Shandong,China |
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| Abstract: | In this article we reviews, the recent advances of pharmacokinetic-pharmacodynamic model reviews in building model and the application in pharmacology, toxicology, clinical trials, and predicts the development of the PK-PD model in the future. |
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| Keywords: | pharmacokinetics pharmacodynamics pharmacokinetic-pharmacodynamic model clinical trial |
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