| 新生儿先天性甲状腺功能减退症筛查中TSH切值的探讨 |
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| 引用本文： | 陈肖肖,秦玉峰,曲一平,毛华庆,施玉华,赵正言. 新生儿先天性甲状腺功能减退症筛查中TSH切值的探讨[J]. 中华内分泌代谢杂志, 2008, 24(6) |
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| 作者姓名： | 陈肖肖 秦玉峰 曲一平 毛华庆 施玉华 赵正言 |
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| 作者单位： | 浙江大学医学院附属儿童医院,杭州,310003 |
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| 基金项目： | 浙江省科技厅资助项目 |
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| 摘 要： | 新生儿筛查中发现,TSH水平与先天性甲状腺功能减退症(CH)检出率呈直线正相关.当TSH切值点分别为9、10、15和20 mU/L时,CH阳性检测敏感度分别 99.77%、96.80%、81.25%和71.88%.TSH>9 mU/L是较好的切点.
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| 关 键 词： | 新生儿筛查 甲状腺功能减退症 促甲状腺素 参考值 |
Exploration of cut-off value of TSH during screening of congenital hypothyroidism in the newborns |
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| CHEN Xiao-xiao,QIN Yu-feng,QU Yi-ping,MAO Hua-qing,SHI Yu-hua,ZHAO Zheng-yan. Exploration of cut-off value of TSH during screening of congenital hypothyroidism in the newborns[J]. Chinese Journal of Endocrinology and Metabolism, 2008, 24(6) |
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| Authors: | CHEN Xiao-xiao QIN Yu-feng QU Yi-ping MAO Hua-qing SHI Yu-hua ZHAO Zheng-yan |
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| Abstract: | Positive linear correlation was found between TSH level and detection rate of congenital hypothyroidism (CH). When measured with a cut-off point at 9, 10, 15 and 20 mU/L of TSH, the sensitivity of positive detection rate for CH was 99.77%, 96.80%, 81.25% and 71.88%, respectively. TSH > 9 mU/L seems to be a reasonable cut-off value. |
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| Keywords: | Newborn screening Hypothyroidism Thyrotropin Reference values |
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