中药在肾病综合征激素减量过程中的应用

目的：评价中药在肾病综合征激素减量过程中的作用。方法：将经肾穿刺病理检查确诊并对强的松治疗敏感的原发性肾病综合征１２０例患者随机分为两组。对照组按常规方法撤减激素；观察组在常规方法撤减激素的过程中加用中药治疗。通过观察激素减量过程肾病综征的复发及强的松副作用的发生情况评价中药的疗效。结果：观察组肾病综合征复发率及强的松副作用发生率显著低于对照组（Ｐ〈０．０１）。结论：对激素敏感的肾病综合征在激素减

Assessment on Application of Chinese Herbs in Process of Corticosterone Reduction in Nephrotic Syndrome

Objective: To evaluate the effect of Chinese herbs in the process of corticosterone (CS) reduction in nephrotic syndrome. Methods: One hundred and twenty patients of idiopathic nephrotic syndrome sensitive to prednisone treatment were divided into two groups randomly. The dosage of prednisone used was reduced by routine in both groups but Chinese herbal treatment was added to the treated group in the period of prednisone reduction. The effect of Chinese herbs was estimated by observing the recurrence rate of disease and side effects of prednisone. Results: The recurrence rate of disease and the occurrence rate of side effects of prednisone in the treated group were lesser than that in the control group significantly (P<0 01). Conclusion: Additional Chinese herbs in the process of CS reduction in the treatment of CS sensitive nephrotic syndrome could extenuate markedly the recurrence rate of disease and the side effect of CS reduction.