脑电生物反馈对脑卒中后心理障碍及日常生活能力的影响

目的探讨脑电生物反馈联合抗抑郁药物对脑卒中后抑郁、焦虑和认知功能干预效果,以及对日常生活能力的影响。方法共选取90例脑卒中后抑郁、焦虑伴认知障碍患者,将其随机分为对照组和治疗组,对照组给予氟西汀20mg/d,治疗组在应用氟西汀的同时,给予脑电生物反馈治疗。两组患者均在治疗前及治疗4周后(治疗后)分别采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、简易精神状态检查(MMSE)和改良的Barthel指数(MBI)评定患者的抑郁、焦虑状态、认知功能和日常生活能力。结果治疗后,治疗组HAMD、HAMA、MMSE和Barthel指数(MBI)评分分别为(8.76±4.98)、(7.02±2.82)、(22.27±3.00)和(56.64±11.99),与对照组(11.42±5.66)、(8.98±4.02)、(19.42±3.23)和(49.13±10.48)比较,差异有统计学意义(P0.05)。结论在抗抑郁药物的基础上辅以脑电生物反馈治疗能进一步改善脑卒中患者的抑郁、焦虑情绪和认知功能,同时由于患者心理状态的改善,对患者日常生活能力的提高也有促进作用。

Impact of EEG Biofeedback on Psychological Disorder Efficacy and Ability of Daily Living of Post-stroke

Objective To investigate the intervention effect of EEG biofeedback treatment combined with antidepressant drugs to pa -tients with depression,anxiety,cognitive dysfunction after stroke and its impact on daily living of post -stroke.Methods As observed objects,90 patients with post -stroke depression and anxiety associated with cognitive dysfunction were randomly divided into control group and treatment group .Patients of the control group were given fluoxetine 20mg/d and the treatment group accepted further EEG bio-feedback therapy while in the application of fluoxetine.Hamilton Depression Scale（HAMD）,Hamilton Anxiety Scale（HAMA）,Mini Mental State Examination（MMSE） and Modified Barthel index（MBI） were respectively used to assess the degree of depression ,anxiety, cognitive function and the ability of ADL before treatment and after treatment for 4 weeks.Results After treatment,scores of HAMD, HAMA,MMSE and MBI in the treatment group were respectively （8.76 ±4.98ab）,（7.02 ±2.82ab）,（22.27 ±3.00ab） and（56.64 ± 11.99ab） while they were respectively（11.42 ±5.66a）,（8.98 ±4.02a）,（19.42 ±3.23a） and（49.13 ±10.48a） in the control group,there were significant differences between the two groups （P〈0.05）.The cure rate and effective rate were respectively 17.14%and 54.29%in the treatment group,while in the control group were 2.86%and 20.00%respectively.Conclusion The therapy of anti-depressant drugs combined with EEG biofeedback treatment can further relieve depression ,anxiety and cognitive function in stroke pa-tients.Because of relief of mentation ,the patients＇ability of daily living has been improved .So the combination therapy should be widely applied.