Effects of ginsenosides on vascular reactivity in rat cerebral and renal arteries |
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Authors: | WONG Wing-tak LEUNG Fung-ping YUNG Lai-hang TIAN Xiao-yu WONG Ricky Ngok Shun HUANG Yu |
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Affiliation: | WONG Wing-tak1,LEUNG Fung-ping1,YUNG Lai-hang1,TIAN Xiao-yu1,WONG Ricky Ngok Shun2,HUANG Yu1(1.Department of Physiology,Chinese University of Hong Kong,Hong Kong,China,2.Department of Biology,Hong Kong Baptist University,China) |
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Abstract: | Objective To investigate possible mechanisms underlying the antioxidant property(1)and the in vitro vasodilator effects(2)of the two ginsenosides,Rb1 and Rg1,in isolated rat renal and cerebral arteries.Methods Arterial rings were mounted in a multi-channel myograph for recording of isometric tension.To examine the antioxidant activity,some rings were exposed to a free radical-generating reaction(hypoxanthine and xanthine oxidase)with and without pre-treatment with ginsenosides.The calcium antagonistic effec... |
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Keywords: | ginsenosides endothelial cells relaxation |
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