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Alteration of esophageal pressure in sleep-disordered breathing
Authors:AKIRA MIKAMI MD    TAKUYA WATANABE MD    MASAMICHI MOTONISHI MD    HIDEHARU HONDA MD    KYOKO KYOTANI MD    SHIGEHIKO URUHA MD    KIYOJI TERASHIMA MD    YOSHIO TESHIMA MD  YOSHIRO SUGITA MD
Institution:Department of Neuropsychiatry, Osaka University Medical School;Department of Medical Science III, School of Health and Sport Sciences, Osaka University, Osaka, Japan
Abstract:Abstract We investigated the alteration of esophageal pressure (Pes) in 10 patients with upper-airway sleep-disordered breathing (UASDB) and the relationship among Pes, breathing patterns and EEG arousals. Increased negative Pes without apnea or hypopnea, appeared not only in upper airway resistance syndrome but also in obstructive sleep apnea syndrome. This phenomenon produced frequent EEG microarousals leading to sleep fragmentation and daytime sleepiness. Moreover, increased negative Pes occasionally continued for more than 20 min without an EEG arousal, which might be considered to be one of the factors to cause complications of UASDB.
Keywords:breathing-related EEG arousal  esophageal pressure  obstructive sleep apnea syndrome  sleep-disordered breathing  sleep fragmentation  upper airway resistance syndrome
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