中西医结合削减甲状腺激素用量改善甲状腺功能临床观察

目的观察中西医结合治疗甲状腺功能减退症的临床疗效及削减甲状腺激素用量、改善甲状腺功能情况。方法将甲状腺功能减低症患者随机分为治疗组(32例)和对照组(30例)。两组均予以甲状腺激素治疗;治疗组在保证疗效的前提下,最大限度地渐减甲状腺激素用量,同时加用温阳益气、化瘀利湿汤药,并比较两组患者主要临床症状改善情况、甲状腺功能变化情况及激素不良反应增减情况。结果两组间总有效率无明显差异,但显效率差异明显;与对照组相比,治疗组症状改善明显且快,增高的促甲状腺激素(TSH)下降幅度及降低的T3、T4提高幅度既大又快,激素的不良反应消除。结论中西医结合治疗甲状腺功能减低症,可尽快改善症状,促进甲状腺功能恢复,在削减激素用量的情况下仍能获得满意疗效。

Clinical Observation on Reduction of Thyroid Hormone and Improvement of Thyroid Function by Combination of Traditional Chinese and Western Medicine

Objective To observe the clinical effect of combination of traditional Chinese and western medicine to treat the hypothyreosis disease, and dosage reduction of thyroid hormone and improvement of thyroid function. Method The patient of hypothyreosis were divided into two groups, 32 cases in treatment group and 30 cases in control group. Both groups were treated with thyroid hormone. The treatment group reduced the dosage of thyroid hormone to high limit in the prerequisite of ensuring the curative effect, and was given the decoction of warming Yang and benefiting Qi, removing stasis and dampness. Then compare the improvement of main clinical symptoms of the two groups, as well as their function of thyroid and side effects of hormone. Result There was no significant difference in total effective rate between two groups, while there was notable diffenrence in excellent effective rate. Compare with the control group, the symptoms of the treatment group were improved obviously and rapidly, the falling extent of the increasing thyroid-stimulating hormone (TSH) was large and quick, so as the enhancing extent of the decreasing T3 and T4, the sid effect of hormone was eradicated. Conclusions To treat the hypothyreosis disease, combination of traditional Chinese and western medicine can improve the symptom quickly, promote the recovery of thyroid function, and get the satisfactory curative effect, even if reduce the dosage of hormone.